rs1805005
MC1Rrs1805005 is a single-nucleotide polymorphism (SNP) in the MC1R gene. Genespiral reads it in the Health & Wellness and Appearance analyses to describe Motion Sickness Susceptibility and Sun Sensitivity.
- Gene
- MC1R
- Alleles
- G / T
- Genotypes
- GG, GT, TT
- Traits
- 2 traits across 2 analyses
An rsID such as rs1805005 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of GG, GT, TT. The order of the two letters carries no meaning, so GT and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Motion Sickness Susceptibility
Sensory and Neurological · Part of the Health & Wellness analysis
May affect vestibular response, influencing susceptibility to motion sickness.
| Genotype | Association |
|---|---|
| GG | Higher Susceptibility |
| GT | Moderate Susceptibility |
| TT | Lower Susceptibility |
- Summary
- MC1R variations are associated with differences in motion sickness sensitivity.
- Scientific insights
- 'GG' alleles may indicate higher sensitivity to motion-induced nausea.
- Lifestyle tips
- Focusing on the horizon can help mitigate symptoms during travel.
Sun Sensitivity
Personal Traits · Part of the Appearance analysis
Influences how skin reacts to UV exposure.
| Genotype | Association |
|---|---|
| GG | Less Sensitive |
| GT | Moderate Sensitivity |
| TG | Moderate Sensitivity |
| TT | More Sensitive |
- Summary
- Variations affect tanning ability and sunburn risk.
- Scientific insights
- The 'TT' genotype is associated with higher sun sensitivity and risk of sunburn.
- Lifestyle tips
- Use high-SPF sunscreen and protective clothing if you are sun-sensitive.
Check your genotype at rs1805005
Load your raw DNA file and Genespiral looks up rs1805005 along with every other marker in the Health & Wellness and Appearance analyses. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Motion Sickness Susceptibility and Sun Sensitivity in your results.
Related
More markers from Health & Wellness and Appearance
- rs334 (HBB) - Malaria Resistance
- rs1042725 (HMGA2) - Height Potential and Height
- rs1800562 (HFE) - Hereditary Hemochromatosis Risk
- rs2282679 (GC) - Vitamin D Levels and Vitamin D Deficiency Risk
- rs6983267 (CASC8/CCAT2 (8q24)) - Colorectal Cancer Risk
- rs11209026 (IL23R) - Inflammatory Bowel Disease Protection (IL23R)
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs1805005 - NCBI
- rs1805005 variant page - Ensembl
- rs1805005 summary - SNPedia
- Clinical significance records for rs1805005 - ClinVar
- MC1R gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.