rs2282679
GCrs2282679 is a single-nucleotide polymorphism (SNP) in the GC gene. Genespiral reads it in the Health & Wellness analysis to describe Vitamin D Levels and Vitamin D Deficiency Risk.
- Gene
- GC
- Alleles
- A / G
- Genotypes
- AA, AG, GG
- Traits
- 2 traits across 1 analysis
An rsID such as rs2282679 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of AA, AG, GG. The order of the two letters carries no meaning, so AG and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Vitamin D Levels
Metabolic and Nutritional · Part of the Health & Wellness analysis
Influences the transport and bioavailability of vitamin D in the bloodstream.
| Genotype | Association |
|---|---|
| AA | Lower Levels |
| AG | Average Levels |
| GG | Higher Levels |
- Summary
- GC gene variations affect vitamin D levels, impacting bone and immune health.
- Scientific insights
- 'AA' genotype individuals may have lower circulating vitamin D and benefit from supplementation.
- Lifestyle tips
- Sun exposure and dietary sources can help maintain adequate vitamin D levels.
Vitamin D Deficiency Risk
Metabolic and Nutritional · Part of the Health & Wellness analysis
Affects vitamin D binding and bioavailability, influencing deficiency risk.
| Genotype | Association |
|---|---|
| AA | Higher Risk |
| AG | Moderate Risk |
| GG | Lower Risk |
- Summary
- GC gene variations affect circulating vitamin D levels and risk of deficiency.
- Scientific insights
- 'AA' genotype may have lower vitamin D levels, increasing deficiency risk especially in low-sunlight areas.
- Lifestyle tips
- Vitamin D supplementation and moderate sun exposure can help maintain adequate levels.
Check your genotype at rs2282679
Load your raw DNA file and Genespiral looks up rs2282679 along with every other marker in the Health & Wellness analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Vitamin D Levels and Vitamin D Deficiency Risk in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs2282679 - NCBI
- rs2282679 variant page - Ensembl
- rs2282679 summary - SNPedia
- Clinical significance records for rs2282679 - ClinVar
- GC gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.