rs174547
FADS1rs174547 is a single-nucleotide polymorphism (SNP) in the FADS1 gene. Genespiral reads it in the Health & Wellness analysis to describe Omega Fatty-Acid Conversion.
- Gene
- FADS1
- Alleles
- C / T
- Genotypes
- CC, CT, TT
- Traits
- 1 trait across 1 analysis
An rsID such as rs174547 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of CC, CT, TT. The order of the two letters carries no meaning, so CT and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Omega Fatty-Acid Conversion
Metabolic and Nutritional · Part of the Health & Wellness analysis
FADS1 encodes a desaturase that converts dietary plant omega-3 and omega-6 fats into longer-chain forms (EPA, arachidonic acid); this variant changes that efficiency.
| Genotype | Association |
|---|---|
| CC | Efficient converter |
| CT | Intermediate |
| TT | Less efficient converter |
- Summary
- FADS1 genotype affects how efficiently the body converts plant-based fatty acids into their active long-chain forms.
- Scientific insights
- The 'CC' genotype converts fatty acids more efficiently; 'TT' individuals convert plant omega-3s (ALA) to EPA/DHA less efficiently.
- Lifestyle tips
- Less-efficient converters may benefit relatively more from preformed EPA/DHA sources such as oily fish or algae oil.
Check your genotype at rs174547
Load your raw DNA file and Genespiral looks up rs174547 along with every other marker in the Health & Wellness analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Omega Fatty-Acid Conversion in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs174547 - NCBI
- rs174547 variant page - Ensembl
- rs174547 summary - SNPedia
- Clinical significance records for rs174547 - ClinVar
- FADS1 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.