rs1799945
HFErs1799945 is a single-nucleotide polymorphism (SNP) in the HFE gene. Genespiral reads it in the Health & Wellness analysis to describe Iron Metabolism and Endurance.
- Gene
- HFE
- Alleles
- C / G
- Genotypes
- GG, GC, CC
- Traits
- 1 trait across 1 analysis
An rsID such as rs1799945 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of GG, GC, CC. The order of the two letters carries no meaning, so GC and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Iron Metabolism and Endurance
Metabolic and Nutritional · Part of the Health & Wellness analysis
Regulates iron absorption, affecting endurance potential and oxygen transport.
| Genotype | Association |
|---|---|
| GG | Higher Iron Levels |
| GC | Moderate Iron Levels |
| CC | Lower Iron Levels |
- Summary
- HFE gene variations impact iron metabolism, important for athletic endurance.
- Scientific insights
- 'GG' genotype may be associated with higher iron stores, beneficial for endurance activities.
- Lifestyle tips
- Iron-rich foods can support optimal oxygen transport during endurance training.
Check your genotype at rs1799945
Load your raw DNA file and Genespiral looks up rs1799945 along with every other marker in the Health & Wellness analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Iron Metabolism and Endurance in your results.
Related
Other markers in HFE
- rs1800562 - Hereditary Hemochromatosis Risk
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs1799945 - NCBI
- rs1799945 variant page - Ensembl
- rs1799945 summary - SNPedia
- Clinical significance records for rs1799945 - ClinVar
- HFE gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.