rs2981582
FGFR2rs2981582 is a single-nucleotide polymorphism (SNP) in the FGFR2 gene. Genespiral reads it in the Health & Wellness analysis to describe Breast Cancer Risk.
- Gene
- FGFR2
- Alleles
- A / G
- Genotypes
- AA, AG, GG
- Traits
- 1 trait across 1 analysis
An rsID such as rs2981582 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of AA, AG, GG. The order of the two letters carries no meaning, so AG and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Breast Cancer Risk
Cancer Risk · Part of the Health & Wellness analysis
Encodes a protein involved in cell growth and division, impacting breast cancer risk.
| Genotype | Association |
|---|---|
| AA | Higher Risk |
| AG | Moderate Risk |
| GG | Lower Risk |
- Summary
- FGFR2 gene variations contribute to an individual’s susceptibility to breast cancer.
- Scientific insights
- 'AA' genotype is associated with an increased risk of developing breast cancer.
- Lifestyle tips
- Regular screenings and a healthy lifestyle can help manage breast cancer risk.
Check your genotype at rs2981582
Load your raw DNA file and Genespiral looks up rs2981582 along with every other marker in the Health & Wellness analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Breast Cancer Risk in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs2981582 - NCBI
- rs2981582 variant page - Ensembl
- rs2981582 summary - SNPedia
- Clinical significance records for rs2981582 - ClinVar
- FGFR2 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.