rs7501331
BCO1rs7501331 is a single-nucleotide polymorphism (SNP) in the BCO1 gene. Genespiral reads it in the Health & Wellness analysis to describe Beta-Carotene Conversion.
- Gene
- BCO1
- Alleles
- C / T
- Genotypes
- CC, CT, TT
- Traits
- 1 trait across 1 analysis
An rsID such as rs7501331 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of CC, CT, TT. The order of the two letters carries no meaning, so CT and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Beta-Carotene Conversion
Metabolic and Nutritional · Part of the Health & Wellness analysis
The BCO1 enzyme converts dietary beta-carotene (provitamin A) into active vitamin A; this variant lowers its efficiency.
| Genotype | Association |
|---|---|
| CC | Efficient converter |
| CT | Moderately reduced conversion |
| TT | Reduced converter |
- Summary
- BCO1 variations affect how efficiently plant-based beta-carotene is converted into usable vitamin A.
- Scientific insights
- Carriers of the 'T' allele convert beta-carotene less efficiently, so 'TT' individuals may have higher circulating beta-carotene and rely more on preformed vitamin A sources.
- Lifestyle tips
- Reduced converters can obtain preformed vitamin A (retinol) from sources such as eggs, dairy, and fish, in moderation.
Check your genotype at rs7501331
Load your raw DNA file and Genespiral looks up rs7501331 along with every other marker in the Health & Wellness analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Beta-Carotene Conversion in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs7501331 - NCBI
- rs7501331 variant page - Ensembl
- rs7501331 summary - SNPedia
- Clinical significance records for rs7501331 - ClinVar
- BCO1 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.