rs683
IRF4rs683 is a single-nucleotide polymorphism (SNP) in the IRF4 gene. Genespiral reads it in the Aging & Longevity analysis to describe Gray Hair Onset.
- Gene
- IRF4
- Alleles
- C / T
- Genotypes
- CC, CT, TT
- Traits
- 1 trait across 1 analysis
An rsID such as rs683 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of CC, CT, TT. The order of the two letters carries no meaning, so CT and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Gray Hair Onset
Hair Aging · Part of the Aging & Longevity analysis
Influences melanin production in hair follicles.
| Genotype | Association |
|---|---|
| CC | Typical onset of graying |
| CT | Slight variation in onset |
| TT | Possible earlier onset |
- Summary
- One of several genes associated with hair graying timing.
- Scientific insights
- Multiple factors beyond genetics influence graying timing.
- Lifestyle tips
- Nutritional deficiencies and stress can influence hair graying.
Check your genotype at rs683
Load your raw DNA file and Genespiral looks up rs683 along with every other marker in the Aging & Longevity analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Gray Hair Onset in your results.
Related
Other markers in IRF4
- rs12203592 - Freckles and Hair Graying
More markers from Aging & Longevity
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs683 - NCBI
- rs683 variant page - Ensembl
- rs683 summary - SNPedia
- Clinical significance records for rs683 - ClinVar
- IRF4 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.