rs1800629
TNFrs1800629 is a single-nucleotide polymorphism (SNP) in the TNF gene. Genespiral reads it in the Aging & Longevity analysis to describe Inflammation Response.
- Gene
- TNF
- Alleles
- A / G
- Genotypes
- GG, AG, AA
- Traits
- 1 trait across 1 analysis
An rsID such as rs1800629 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of GG, AG, AA. The order of the two letters carries no meaning, so AG and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Inflammation Response
Immune Aging · Part of the Aging & Longevity analysis
Regulates inflammatory signaling.
| Genotype | Association |
|---|---|
| GG | Typical inflammatory response |
| AG | Slightly modified response |
| AA | Modified inflammatory response |
- Summary
- Affects baseline inflammation levels.
- Scientific insights
- Diet and lifestyle strongly influence expression.
- Lifestyle tips
- Anti-inflammatory lifestyle benefits all genotypes.
Check your genotype at rs1800629
Load your raw DNA file and Genespiral looks up rs1800629 along with every other marker in the Aging & Longevity analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Inflammation Response in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs1800629 - NCBI
- rs1800629 variant page - Ensembl
- rs1800629 summary - SNPedia
- Clinical significance records for rs1800629 - ClinVar
- TNF gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.