rs362584
SLC6A4rs362584 is a single-nucleotide polymorphism (SNP) in the SLC6A4 gene. Genespiral reads it in the Personality analysis to describe Neuroticism.
- Gene
- SLC6A4
- Alleles
- A / G
- Genotypes
- AA, AG, GG
- Traits
- 1 trait across 1 analysis
An rsID such as rs362584 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of AA, AG, GG. The order of the two letters carries no meaning, so AG and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Neuroticism
Personality Traits · Part of the Personality analysis
Associated with serotonin transporter efficiency, impacting mood and emotional regulation.
| Genotype | Association |
|---|---|
| AA | Higher neuroticism |
| AG | Moderate neuroticism |
| GG | Lower neuroticism |
- Summary
- SLC6A4 gene variants influence serotonin reuptake, affecting susceptibility to stress and anxiety.
- Scientific insights
- The 'AA' genotype may lead to a heightened response to stressful situations.
- Lifestyle tips
- Mindfulness practices can help manage neurotic tendencies and improve emotional resilience.
Check your genotype at rs362584
Load your raw DNA file and Genespiral looks up rs362584 along with every other marker in the Personality analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Neuroticism in your results.
Related
Other markers in SLC6A4
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs362584 - NCBI
- rs362584 variant page - Ensembl
- rs362584 summary - SNPedia
- Clinical significance records for rs362584 - ClinVar
- SLC6A4 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.