rs2740231
SLC6A4rs2740231 is a single-nucleotide polymorphism (SNP) in the SLC6A4 gene. Genespiral reads it in the Personality analysis to describe Fear Response.
- Gene
- SLC6A4
- Alleles
- G / T
- Genotypes
- GG, GT, TT
- Traits
- 1 trait across 1 analysis
An rsID such as rs2740231 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of GG, GT, TT. The order of the two letters carries no meaning, so GT and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Fear Response
Behavioral Traits · Part of the Personality analysis
Involved in serotonin transport affecting fear processing and anxiety.
| Genotype | Association |
|---|---|
| GG | Higher fear response |
| GT | Moderate fear response |
| TT | Lower fear response |
- Summary
- SLC6A4 variants influence the extent of one's fear response to stressors.
- Scientific insights
- Individuals with 'GG' may experience stronger or more immediate fear reactions.
- Lifestyle tips
- Practicing breathing exercises can help manage fear responses.
Check your genotype at rs2740231
Load your raw DNA file and Genespiral looks up rs2740231 along with every other marker in the Personality analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Fear Response in your results.
Related
Other markers in SLC6A4
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs2740231 - NCBI
- rs2740231 variant page - Ensembl
- rs2740231 summary - SNPedia
- Clinical significance records for rs2740231 - ClinVar
- SLC6A4 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.