rs2254298
OXTRrs2254298 is a single-nucleotide polymorphism (SNP) in the OXTR gene. Genespiral reads it in the Personality analysis to describe Attachment Style and Compassion Fatigue.
- Gene
- OXTR
- Alleles
- A / G
- Genotypes
- GG, AG, AA
- Traits
- 2 traits across 1 analysis
An rsID such as rs2254298 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of GG, AG, AA. The order of the two letters carries no meaning, so AG and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Attachment Style
Social Traits · Part of the Personality analysis
Linked to oxytocin receptor function, impacting attachment behavior and bonding.
| Genotype | Association |
|---|---|
| GG | Secure attachment style |
| AG | Anxious attachment style |
| AA | Avoidant attachment style |
- Summary
- OXTR gene variations influence attachment styles, which affect interpersonal relationships.
- Scientific insights
- Individuals with 'GG' may be more secure and trusting in their relationships.
- Lifestyle tips
- Building strong communication skills can help improve attachment security.
Compassion Fatigue
Emotional Traits · Part of the Personality analysis
Associated with oxytocin receptors, influencing empathy and emotional fatigue in helping roles.
| Genotype | Association |
|---|---|
| GG | More susceptible |
| AG | Moderately susceptible |
| AA | Less susceptible |
- Summary
- OXTR gene variations may impact susceptibility to compassion fatigue, especially in caregiving roles.
- Scientific insights
- Individuals with 'GG' may feel emotionally drained more easily in response to others' suffering.
- Lifestyle tips
- Regular self-care and boundary-setting practices can help mitigate compassion fatigue.
Check your genotype at rs2254298
Load your raw DNA file and Genespiral looks up rs2254298 along with every other marker in the Personality analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Attachment Style and Compassion Fatigue in your results.
Related
Other markers in OXTR
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs2254298 - NCBI
- rs2254298 variant page - Ensembl
- rs2254298 summary - SNPedia
- Clinical significance records for rs2254298 - ClinVar
- OXTR gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.