rs6311
HTR2Ars6311 is a single-nucleotide polymorphism (SNP) in the HTR2A gene. Genespiral reads it in the Personality analysis to describe Agreeableness.
- Gene
- HTR2A
- Alleles
- C / T
- Genotypes
- TT, TC, CC
- Traits
- 1 trait across 1 analysis
An rsID such as rs6311 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of TT, TC, CC. The order of the two letters carries no meaning, so TC and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Agreeableness
Personality Traits · Part of the Personality analysis
Linked to serotonin receptors influencing emotional regulation and social behavior.
| Genotype | Association |
|---|---|
| TT | More agreeable |
| TC | Moderately agreeable |
| CC | Less agreeable |
- Summary
- HTR2A variants may modulate empathy and cooperativeness, impacting agreeableness.
- Scientific insights
- Individuals with 'TT' tend to show greater empathy and warmth in social interactions.
- Lifestyle tips
- Practicing empathy can enhance agreeableness in social and professional settings.
Check your genotype at rs6311
Load your raw DNA file and Genespiral looks up rs6311 along with every other marker in the Personality analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Agreeableness in your results.
Related
Other markers in HTR2A
- rs6313 - Emotional Sensitivity and Aggressiveness
More markers from Personality
- rs4680 (COMT) - Pain Sensitivity and Extraversion
- rs7412 (APOE) - Attention to Detail and Risk of Alzheimer's Disease
- rs644148 (CHRNA4) - Openness to Experience
- rs1338047 (GABRB1) - Cognitive Empathy
- rs2254298 (OXTR) - Attachment Style and Compassion Fatigue
- rs3796863 (CD38) - Tendency to Anthropomorphize
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs6311 - NCBI
- rs6311 variant page - Ensembl
- rs6311 summary - SNPedia
- Clinical significance records for rs6311 - ClinVar
- HTR2A gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.