rs1229984
ADH1Brs1229984 is a single-nucleotide polymorphism (SNP) in the ADH1B gene. Genespiral reads it in the Health & Wellness analysis to describe Alcohol Dependence.
- Gene
- ADH1B
- Alleles
- A / G
- Genotypes
- AA, AG, GG
- Traits
- 1 trait across 1 analysis
An rsID such as rs1229984 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of AA, AG, GG. The order of the two letters carries no meaning, so AG and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Alcohol Dependence
Addiction and Substance Response · Part of the Health & Wellness analysis
Encodes an enzyme that metabolizes alcohol, impacting risk of alcohol dependence.
| Genotype | Association |
|---|---|
| AA | Lower Risk |
| AG | Moderate Risk |
| GG | Increased Risk |
- Summary
- ADH1B gene variations influence an individual’s predisposition to alcohol dependence.
- Scientific insights
- 'GG' genotype is associated with an increased risk of alcohol dependence due to slower alcohol breakdown.
- Lifestyle tips
- Limiting alcohol intake and seeking support may help manage dependence risk.
Check your genotype at rs1229984
Load your raw DNA file and Genespiral looks up rs1229984 along with every other marker in the Health & Wellness analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Alcohol Dependence in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs1229984 - NCBI
- rs1229984 variant page - Ensembl
- rs1229984 summary - SNPedia
- Clinical significance records for rs1229984 - ClinVar
- ADH1B gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.