rs1061170
CFHrs1061170 is a single-nucleotide polymorphism (SNP) in the CFH gene. Genespiral reads it in the Health & Wellness analysis to describe Age-Related Macular Degeneration Risk.
- Gene
- CFH
- Alleles
- C / T
- Genotypes
- CC, CT, TT
- Traits
- 1 trait across 1 analysis
An rsID such as rs1061170 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of CC, CT, TT. The order of the two letters carries no meaning, so CT and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Age-Related Macular Degeneration Risk
Eye Health · Part of the Health & Wellness analysis
Plays a role in immune response in the eye, affecting risk of macular degeneration.
| Genotype | Association |
|---|---|
| CC | Increased Risk |
| CT | Moderate Risk |
| TT | Lower Risk |
- Summary
- CFH variations are associated with risk of age-related macular degeneration (AMD).
- Scientific insights
- 'CC' genotype is linked to higher risk of AMD, especially in older adults.
- Lifestyle tips
- Consuming leafy greens can help support eye health over time.
Check your genotype at rs1061170
Load your raw DNA file and Genespiral looks up rs1061170 along with every other marker in the Health & Wellness analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Age-Related Macular Degeneration Risk in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs1061170 - NCBI
- rs1061170 variant page - Ensembl
- rs1061170 summary - SNPedia
- Clinical significance records for rs1061170 - ClinVar
- CFH gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.