rs6313
HTR2Ars6313 is a single-nucleotide polymorphism (SNP) in the HTR2A gene. Genespiral reads it in the Personality analysis to describe Emotional Sensitivity, Aggressiveness, Sensitivity to Criticism and Sensation Avoidance.
- Gene
- HTR2A
- Alleles
- C / T
- Genotypes
- CC, CT, TT
- Traits
- 4 traits across 1 analysis
An rsID such as rs6313 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of CC, CT, TT. The order of the two letters carries no meaning, so CT and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Emotional Sensitivity
Emotional Traits · Part of the Personality analysis
Involved in serotonin receptors, impacting emotional response and sensitivity.
| Genotype | Association |
|---|---|
| CC | Higher emotional sensitivity |
| CT | Moderate sensitivity |
| TT | Lower sensitivity |
- Summary
- Variations in HTR2A may influence how intensely emotions are felt and processed.
- Scientific insights
- Individuals with 'CC' might experience emotions more intensely and empathetically.
- Lifestyle tips
- Practicing self-reflection and emotional regulation can help manage heightened sensitivity.
Aggressiveness
Behavioral Traits · Part of the Personality analysis
Influences serotonin receptors involved in impulse control and aggression.
| Genotype | Association |
|---|---|
| TT | Higher aggressiveness |
| TC | Moderate aggressiveness |
| CC | Lower aggressiveness |
- Summary
- HTR2A variants may contribute to differences in impulsivity and aggressive behavior.
- Scientific insights
- Those with 'TT' may have a stronger reaction to perceived threats or stress.
- Lifestyle tips
- Practicing emotional regulation can help manage aggressive impulses effectively.
Sensitivity to Criticism
Emotional Traits · Part of the Personality analysis
Influences serotonin receptor function, affecting emotional processing and response to feedback.
| Genotype | Association |
|---|---|
| CC | More sensitive to criticism |
| CT | Moderately sensitive |
| TT | Less sensitive to criticism |
- Summary
- HTR2A gene variations may impact one's sensitivity to feedback and social evaluation.
- Scientific insights
- Individuals with 'CC' may experience criticism more intensely, affecting self-esteem.
- Lifestyle tips
- Building resilience through self-compassion can help manage sensitivity to criticism.
Sensation Avoidance
Behavioral Traits · Part of the Personality analysis
Involved in serotonin receptor function, impacting responses to intense sensory experiences.
| Genotype | Association |
|---|---|
| TT | Higher avoidance |
| CT | Moderate avoidance |
| CC | Lower avoidance |
- Summary
- HTR2A gene variations can affect an individual's tendency to avoid stimulating or overwhelming sensory environments.
- Scientific insights
- Individuals with 'TT' may find sensory-rich environments more overwhelming and seek quieter spaces.
- Lifestyle tips
- Practicing mindfulness in controlled sensory environments can help manage sensation avoidance.
Check your genotype at rs6313
Load your raw DNA file and Genespiral looks up rs6313 along with every other marker in the Personality analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Emotional Sensitivity and Aggressiveness in your results.
Related
Other markers in HTR2A
- rs6311 - Agreeableness
More markers from Personality
- rs4680 (COMT) - Pain Sensitivity and Extraversion
- rs7412 (APOE) - Attention to Detail and Risk of Alzheimer's Disease
- rs644148 (CHRNA4) - Openness to Experience
- rs1338047 (GABRB1) - Cognitive Empathy
- rs2254298 (OXTR) - Attachment Style and Compassion Fatigue
- rs3796863 (CD38) - Tendency to Anthropomorphize
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs6313 - NCBI
- rs6313 variant page - Ensembl
- rs6313 summary - SNPedia
- Clinical significance records for rs6313 - ClinVar
- HTR2A gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.