rs7412
APOErs7412 is a single-nucleotide polymorphism (SNP) in the APOE gene. Genespiral reads it in the Personality and Learning & Cognition analyses to describe Attention to Detail and Risk of Alzheimer's Disease.
- Gene
- APOE
- Alleles
- C / T
- Genotypes
- CC, CT, TT
- Traits
- 2 traits across 2 analyses
An rsID such as rs7412 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of CC, CT, TT. The order of the two letters carries no meaning, so CT and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Attention to Detail
Cognitive Traits · Part of the Personality analysis
Linked to cognitive function, APOE variations may impact attention to detail and precision.
| Genotype | Association |
|---|---|
| CC | Higher attention to detail |
| CT | Moderate attention to detail |
| TT | Lower attention to detail |
- Summary
- APOE gene variants influence attention to detail, possibly affecting cognitive tasks requiring precision.
- Scientific insights
- Individuals with 'CC' may excel in tasks that require careful analysis and attention to detail.
- Lifestyle tips
- Training in focus-oriented activities can further improve attention to detail.
Risk of Alzheimer's Disease
Memory · Part of the Learning & Cognition analysis
Apolipoprotein E gene variant influencing Alzheimer’s disease risk.
| Genotype | Association |
|---|---|
| CC | Higher risk of Alzheimer's |
| CT | Moderate risk |
| TT | Lower risk of Alzheimer's |
- Summary
- Variations in the APOE gene affect the risk of developing Alzheimer’s, impacting memory.
- Scientific insights
- Individuals with the 'CC' genotype may have an increased risk of Alzheimer’s disease.
- Lifestyle tips
- Cognitive engagement and a healthy lifestyle can help reduce risk.
Check your genotype at rs7412
Load your raw DNA file and Genespiral looks up rs7412 along with every other marker in the Personality and Learning & Cognition analyses. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Attention to Detail and Risk of Alzheimer's Disease in your results.
Related
Other markers in APOE
- rs429358 - Emotional Resilience and Risk of Memory Decline with Age
More markers from Personality and Learning & Cognition
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs7412 - NCBI
- rs7412 variant page - Ensembl
- rs7412 summary - SNPedia
- Clinical significance records for rs7412 - ClinVar
- APOE gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.