rs6296
HTR1Ars6296 is a single-nucleotide polymorphism (SNP) in the HTR1A gene. Genespiral reads it in the Personality analysis to describe Harm Avoidance.
- Gene
- HTR1A
- Alleles
- C / G
- Genotypes
- GG, CG, CC
- Traits
- 1 trait across 1 analysis
An rsID such as rs6296 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of GG, CG, CC. The order of the two letters carries no meaning, so CG and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Harm Avoidance
Behavioral Traits · Part of the Personality analysis
Linked to serotonin receptors involved in fear and anxiety response.
| Genotype | Association |
|---|---|
| GG | Higher harm avoidance |
| CG | Moderate harm avoidance |
| CC | Lower harm avoidance |
- Summary
- HTR1A gene variations can impact sensitivity to potential threats or dangers.
- Scientific insights
- Individuals with 'GG' may be more cautious and avoid risky situations.
- Lifestyle tips
- Practicing stress-reduction techniques can help manage heightened harm avoidance.
Check your genotype at rs6296
Load your raw DNA file and Genespiral looks up rs6296 along with every other marker in the Personality analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Harm Avoidance in your results.
Related
Other markers in HTR1A
- rs6295 - Mood Regulation
More markers from Personality
- rs4680 (COMT) - Pain Sensitivity and Extraversion
- rs7412 (APOE) - Attention to Detail and Risk of Alzheimer's Disease
- rs644148 (CHRNA4) - Openness to Experience
- rs1338047 (GABRB1) - Cognitive Empathy
- rs2254298 (OXTR) - Attachment Style and Compassion Fatigue
- rs3796863 (CD38) - Tendency to Anthropomorphize
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs6296 - NCBI
- rs6296 variant page - Ensembl
- rs6296 summary - SNPedia
- Clinical significance records for rs6296 - ClinVar
- HTR1A gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.