rs6295
HTR1Ars6295 is a single-nucleotide polymorphism (SNP) in the HTR1A gene. Genespiral reads it in the Personality analysis to describe Mood Regulation.
- Gene
- HTR1A
- Alleles
- C / G
- Genotypes
- GG, CG, CC
- Traits
- 1 trait across 1 analysis
An rsID such as rs6295 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of GG, CG, CC. The order of the two letters carries no meaning, so CG and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Mood Regulation
Emotional Traits · Part of the Personality analysis
Influences serotonin receptors involved in mood and emotional regulation.
| Genotype | Association |
|---|---|
| GG | Better mood regulation |
| CG | Moderate mood regulation |
| CC | Poorer mood regulation |
- Summary
- Variants in HTR1A impact serotonin signaling, affecting an individual's capacity to regulate mood.
- Scientific insights
- Individuals with 'GG' may exhibit greater emotional resilience and stability.
- Lifestyle tips
- Regular physical activity and mindfulness can support mood regulation.
Check your genotype at rs6295
Load your raw DNA file and Genespiral looks up rs6295 along with every other marker in the Personality analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Mood Regulation in your results.
Related
Other markers in HTR1A
- rs6296 - Harm Avoidance
More markers from Personality
- rs4680 (COMT) - Pain Sensitivity and Extraversion
- rs7412 (APOE) - Attention to Detail and Risk of Alzheimer's Disease
- rs644148 (CHRNA4) - Openness to Experience
- rs1338047 (GABRB1) - Cognitive Empathy
- rs2254298 (OXTR) - Attachment Style and Compassion Fatigue
- rs3796863 (CD38) - Tendency to Anthropomorphize
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs6295 - NCBI
- rs6295 variant page - Ensembl
- rs6295 summary - SNPedia
- Clinical significance records for rs6295 - ClinVar
- HTR1A gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.