rs61816761
FLGrs61816761 is a single-nucleotide polymorphism (SNP) in the FLG gene. Genespiral reads it in the Pet & Environmental Sensitivity analysis to describe Dust Mite Allergy Sensitivity.
- Gene
- FLG
- Alleles
- A / G
- Genotypes
- AA, AG, GG
- Traits
- 1 trait across 1 analysis
An rsID such as rs61816761 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of AA, AG, GG. The order of the two letters carries no meaning, so AG and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Dust Mite Allergy Sensitivity
Indoor Allergen Response · Part of the Pet & Environmental Sensitivity analysis
Filaggrin gene important for skin barrier function.
| Genotype | Association |
|---|---|
| AA | Higher risk of dust mite allergies |
| AG | Moderate risk |
| GG | Lower risk of dust mite allergies |
- Summary
- Mutations in the FLG gene are associated with atopic dermatitis and increased risk of dust mite allergies.
- Scientific insights
- Individuals with the 'AA' genotype may have impaired skin barrier function, leading to higher sensitivity to dust mites.
- Lifestyle tips
- Maintaining good skin hydration and reducing dust mite exposure can help manage symptoms.
Check your genotype at rs61816761
Load your raw DNA file and Genespiral looks up rs61816761 along with every other marker in the Pet & Environmental Sensitivity analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Dust Mite Allergy Sensitivity in your results.
Related
More markers from Pet & Environmental Sensitivity
- rs20541 (IL13) - Allergic Sensitivity (Including Pet Allergies)
- rs2243250 (IL4) - Pollen Allergy Sensitivity
- rs2569190 (CD14) - Dust and Dust Mite Allergy Sensitivity
- rs7216389 (GSDMB/ORMDL3) - Childhood-Onset Asthma Risk
- rs9273349 (HLA-DQB1) - Mold Allergy Sensitivity
- rs11558538 (HNMT) - Insect Bite Reaction Severity
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs61816761 - NCBI
- rs61816761 variant page - Ensembl
- rs61816761 summary - SNPedia
- Clinical significance records for rs61816761 - ClinVar
- FLG gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.