rs2243250
IL4rs2243250 is a single-nucleotide polymorphism (SNP) in the IL4 gene. Genespiral reads it in the Pet & Environmental Sensitivity analysis to describe Pollen Allergy Sensitivity.
- Gene
- IL4
- Alleles
- C / T
- Genotypes
- TT, CT, CC
- Traits
- 1 trait across 1 analysis
An rsID such as rs2243250 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of TT, CT, CC. The order of the two letters carries no meaning, so CT and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Pollen Allergy Sensitivity
Plant Allergen Response · Part of the Pet & Environmental Sensitivity analysis
Interleukin 4 gene, plays a key role in allergic responses.
| Genotype | Association |
|---|---|
| TT | Higher risk of pollen allergies |
| CT | Moderate risk |
| CC | Lower risk of pollen allergies |
- Summary
- Variations in the IL4 gene can influence susceptibility to pollen-induced allergies.
- Scientific insights
- Individuals with the 'TT' genotype may be more prone to developing pollen allergies.
- Lifestyle tips
- Monitoring pollen counts and taking preventive measures during high pollen seasons can reduce symptoms.
Check your genotype at rs2243250
Load your raw DNA file and Genespiral looks up rs2243250 along with every other marker in the Pet & Environmental Sensitivity analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Pollen Allergy Sensitivity in your results.
Related
More markers from Pet & Environmental Sensitivity
- rs20541 (IL13) - Allergic Sensitivity (Including Pet Allergies)
- rs2569190 (CD14) - Dust and Dust Mite Allergy Sensitivity
- rs7216389 (GSDMB/ORMDL3) - Childhood-Onset Asthma Risk
- rs9273349 (HLA-DQB1) - Mold Allergy Sensitivity
- rs11558538 (HNMT) - Insect Bite Reaction Severity
- rs61816761 (FLG) - Dust Mite Allergy Sensitivity
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs2243250 - NCBI
- rs2243250 variant page - Ensembl
- rs2243250 summary - SNPedia
- Clinical significance records for rs2243250 - ClinVar
- IL4 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.