rs20541
IL13rs20541 is a single-nucleotide polymorphism (SNP) in the IL13 gene. Genespiral reads it in the Pet & Environmental Sensitivity analysis to describe Allergic Sensitivity (Including Pet Allergies).
- Gene
- IL13
- Alleles
- A / G
- Genotypes
- AA, AG, GG
- Traits
- 1 trait across 1 analysis
An rsID such as rs20541 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of AA, AG, GG. The order of the two letters carries no meaning, so AG and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Allergic Sensitivity (Including Pet Allergies)
Animal Allergen Response · Part of the Pet & Environmental Sensitivity analysis
Interleukin 13 gene involved in immune response and IgE production.
| Genotype | Association |
|---|---|
| AA | Higher risk of allergies |
| AG | Moderate risk |
| GG | Lower risk of allergies |
- Summary
- Variations in the IL13 gene are associated with susceptibility to allergic diseases, including pet allergies.
- Scientific insights
- Individuals with the 'AA' genotype may have an increased risk of developing allergies to pets and environmental allergens.
- Lifestyle tips
- Minimizing exposure to known allergens and consulting an allergist can help manage symptoms.
Check your genotype at rs20541
Load your raw DNA file and Genespiral looks up rs20541 along with every other marker in the Pet & Environmental Sensitivity analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Allergic Sensitivity (Including Pet Allergies) in your results.
Related
More markers from Pet & Environmental Sensitivity
- rs2243250 (IL4) - Pollen Allergy Sensitivity
- rs2569190 (CD14) - Dust and Dust Mite Allergy Sensitivity
- rs7216389 (GSDMB/ORMDL3) - Childhood-Onset Asthma Risk
- rs9273349 (HLA-DQB1) - Mold Allergy Sensitivity
- rs11558538 (HNMT) - Insect Bite Reaction Severity
- rs61816761 (FLG) - Dust Mite Allergy Sensitivity
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs20541 - NCBI
- rs20541 variant page - Ensembl
- rs20541 summary - SNPedia
- Clinical significance records for rs20541 - ClinVar
- IL13 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.