rs2231142
ABCG2rs2231142 is a single-nucleotide polymorphism (SNP) in the ABCG2 gene. Genespiral reads it in the Health & Wellness analysis to describe Gout Risk.
- Gene
- ABCG2
- Alleles
- A / C
- Genotypes
- AA, AC, CC
- Traits
- 1 trait across 1 analysis
An rsID such as rs2231142 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of AA, AC, CC. The order of the two letters carries no meaning, so AC and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Gout Risk
Metabolic Disorders · Part of the Health & Wellness analysis
Regulates uric acid transport, influencing gout risk through buildup in joints.
| Genotype | Association |
|---|---|
| AA | Increased Risk |
| AC | Moderate Risk |
| CC | Lower Risk |
- Summary
- ABCG2 gene variations impact the risk of gout, a form of arthritis caused by high uric acid.
- Scientific insights
- 'AA' genotype is associated with a higher likelihood of developing gout.
- Lifestyle tips
- Reducing purine-rich foods and staying hydrated can help manage gout risk.
Check your genotype at rs2231142
Load your raw DNA file and Genespiral looks up rs2231142 along with every other marker in the Health & Wellness analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Gout Risk in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs2231142 - NCBI
- rs2231142 variant page - Ensembl
- rs2231142 summary - SNPedia
- Clinical significance records for rs2231142 - ClinVar
- ABCG2 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.