rs9382445
CHRM2 ABCC9rs9382445 is a single-nucleotide polymorphism (SNP) in the CHRM2 / ABCC9 gene. Genespiral reads it in the Sleep analysis to describe REM vs NREM Sleep Architecture and Sleep Duration.
- Gene
- CHRM2 / ABCC9
- Alleles
- C / T
- Genotypes
- TT, TC, CC
- Traits
- 2 traits across 1 analysis
An rsID such as rs9382445 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of TT, TC, CC. The order of the two letters carries no meaning, so TC and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
REM vs NREM Sleep Architecture
Sleep Patterns · Part of the Sleep analysis
Associated with neurotransmitter signaling, influencing REM/NREM balance.
| Genotype | Association |
|---|---|
| TT | More REM sleep |
| TC | Balanced REM/NREM |
| CC | Less REM sleep |
- Summary
- CHRM2 gene variations may impact the ratio of REM to NREM sleep stages.
- Scientific insights
- 'TT' is linked to increased REM sleep duration compared to 'CC'.
- Lifestyle tips
- Practicing relaxation techniques before bed can promote a balanced sleep architecture.
Sleep Duration
Sleep Traits · Part of the Sleep analysis
Associated with cellular energy regulation, influencing sleep duration needs.
| Genotype | Association |
|---|---|
| CC | Short Sleeper |
| CT | Average Sleeper |
| TT | Long Sleeper |
- Summary
- ABCC9 variations are linked to natural sleep duration, from shorter to longer sleep cycles.
- Scientific insights
- 'CC' genotype individuals tend to require less sleep compared to 'TT' genotype.
- Lifestyle tips
- Maintaining consistent sleep hygiene can optimize sleep quality regardless of genetic predisposition.
Check your genotype at rs9382445
Load your raw DNA file and Genespiral looks up rs9382445 along with every other marker in the Sleep analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find REM vs NREM Sleep Architecture and Sleep Duration in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs9382445 - NCBI
- rs9382445 variant page - Ensembl
- rs9382445 summary - SNPedia
- Clinical significance records for rs9382445 - ClinVar
- CHRM2 gene - NCBI Gene
- ABCC9 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.