rs9357271
BTBD9rs9357271 is a single-nucleotide polymorphism (SNP) in the BTBD9 gene. Genespiral reads it in the Sleep analysis to describe Restless Legs Syndrome.
- Gene
- BTBD9
- Alleles
- C / T
- Genotypes
- TT, TC, CC
- Traits
- 1 trait across 1 analysis
An rsID such as rs9357271 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of TT, TC, CC. The order of the two letters carries no meaning, so TC and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Restless Legs Syndrome
Sleep Disorders · Part of the Sleep analysis
Affects dopamine and iron regulation, influencing the likelihood of RLS.
| Genotype | Association |
|---|---|
| TT | Higher risk of RLS |
| TC | Moderate risk |
| CC | Lower risk |
- Summary
- BTBD9 variations are linked to susceptibility to restless legs syndrome, especially during periods of inactivity.
- Scientific insights
- 'TT' genotype individuals have a higher likelihood of experiencing RLS symptoms, such as leg discomfort at night.
- Lifestyle tips
- Iron-rich foods and regular exercise can help alleviate RLS symptoms.
Check your genotype at rs9357271
Load your raw DNA file and Genespiral looks up rs9357271 along with every other marker in the Sleep analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Restless Legs Syndrome in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs9357271 - NCBI
- rs9357271 variant page - Ensembl
- rs9357271 summary - SNPedia
- Clinical significance records for rs9357271 - ClinVar
- BTBD9 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.