rs228697
PER3rs228697 is a single-nucleotide polymorphism (SNP) in the PER3 gene. Genespiral reads it in the Sleep analysis to describe Susceptibility to Sleep Deprivation.
- Gene
- PER3
- Alleles
- C / T
- Genotypes
- CC, CT, TT
- Traits
- 1 trait across 1 analysis
An rsID such as rs228697 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of CC, CT, TT. The order of the two letters carries no meaning, so CT and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Susceptibility to Sleep Deprivation
Sleep Disorders · Part of the Sleep analysis
Influences sleep-wake resilience, particularly under restricted sleep conditions.
| Genotype | Association |
|---|---|
| CC | More resistant to sleep deprivation |
| CT | Moderate resistance |
| TT | More sensitive to sleep deprivation |
- Summary
- Variations in PER3 gene affect an individual’s response to sleep loss.
- Scientific insights
- 'TT' is associated with increased sensitivity to sleep deprivation, while 'CC' indicates greater resilience.
- Lifestyle tips
- Practicing good sleep hygiene can help manage effects of sleep loss.
Check your genotype at rs228697
Load your raw DNA file and Genespiral looks up rs228697 along with every other marker in the Sleep analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Susceptibility to Sleep Deprivation in your results.
Related
Other markers in PER3
- rs1805319 - Sleep Quality
- rs28381999 - Work Ethic
More markers from Sleep
- rs642961 (IRF6 / PER1) - Lip Thickness and Chronotype (Morning vs Evening Preference)
- rs1801260 (CLOCK) - Sleep-Wake Timing (Circadian Rhythm)
- rs2304672 (HLA-DQB1) - Susceptibility to Sleep Paralysis
- rs5757241 (ADRB1) - Sleep Efficiency
- rs7851725 (GBA) - REM Sleep Behavior Disorder
- rs9900518 (MEIS1) - Insomnia Susceptibility
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs228697 - NCBI
- rs228697 variant page - Ensembl
- rs228697 summary - SNPedia
- Clinical significance records for rs228697 - ClinVar
- PER3 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.