rs7851725
GBArs7851725 is a single-nucleotide polymorphism (SNP) in the GBA gene. Genespiral reads it in the Sleep analysis to describe REM Sleep Behavior Disorder.
- Gene
- GBA
- Alleles
- C / T
- Genotypes
- TT, TC, CC
- Traits
- 1 trait across 1 analysis
An rsID such as rs7851725 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of TT, TC, CC. The order of the two letters carries no meaning, so TC and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
REM Sleep Behavior Disorder
Sleep Disorders · Part of the Sleep analysis
Associated with REM sleep characteristics and control over dream enactment behavior.
| Genotype | Association |
|---|---|
| TT | Increased risk for RBD |
| TC | Moderate risk |
| CC | Lower risk |
- Summary
- Genetic variations in GBA may influence the risk of REM sleep behavior disorder.
- Scientific insights
- 'TT' individuals have a higher likelihood of experiencing RBD, often acting out dreams.
- Lifestyle tips
- Engaging in stress-reducing activities before bed may help reduce symptoms.
Check your genotype at rs7851725
Load your raw DNA file and Genespiral looks up rs7851725 along with every other marker in the Sleep analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find REM Sleep Behavior Disorder in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs7851725 - NCBI
- rs7851725 variant page - Ensembl
- rs7851725 summary - SNPedia
- Clinical significance records for rs7851725 - ClinVar
- GBA gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.