rs7454108
TAGAPrs7454108 is a single-nucleotide polymorphism (SNP) in the TAGAP gene. Genespiral reads it in the Health & Wellness analysis to describe Celiac Disease Risk.
- Gene
- TAGAP
- Alleles
- C / T
- Genotypes
- TT, TC, CC
- Traits
- 1 trait across 1 analysis
An rsID such as rs7454108 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of TT, TC, CC. The order of the two letters carries no meaning, so TC and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Celiac Disease Risk
Autoimmune and Inflammatory Conditions · Part of the Health & Wellness analysis
Involved in immune function, associated with susceptibility to autoimmune diseases.
| Genotype | Association |
|---|---|
| TT | Increased Risk |
| TC | Moderate Risk |
| CC | Lower Risk |
- Summary
- TAGAP gene variations are linked to celiac disease risk by affecting immune responses.
- Scientific insights
- 'TT' genotype may increase susceptibility to celiac disease, especially in individuals with family history.
- Lifestyle tips
- A gluten-free diet is essential for managing symptoms if celiac disease is diagnosed.
Check your genotype at rs7454108
Load your raw DNA file and Genespiral looks up rs7454108 along with every other marker in the Health & Wellness analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Celiac Disease Risk in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs7454108 - NCBI
- rs7454108 variant page - Ensembl
- rs7454108 summary - SNPedia
- Clinical significance records for rs7454108 - ClinVar
- TAGAP gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.