rs2815752
NEGR1rs2815752 is a single-nucleotide polymorphism (SNP) in the NEGR1 gene. Genespiral reads it in the Health & Wellness analysis to describe Obesity Risk.
- Gene
- NEGR1
- Alleles
- A / G
- Genotypes
- GG, AG, AA
- Traits
- 1 trait across 1 analysis
An rsID such as rs2815752 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of GG, AG, AA. The order of the two letters carries no meaning, so AG and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Obesity Risk
Metabolic Disorders · Part of the Health & Wellness analysis
Associated with appetite regulation, affecting risk of obesity.
| Genotype | Association |
|---|---|
| GG | Increased Risk |
| AG | Moderate Risk |
| AA | Lower Risk |
- Summary
- NEGR1 gene variations may influence susceptibility to weight gain and obesity.
- Scientific insights
- 'GG' alleles are linked to a higher risk of obesity, possibly due to increased appetite or caloric intake.
- Lifestyle tips
- Maintaining a balanced diet and regular exercise can help manage obesity risk.
Check your genotype at rs2815752
Load your raw DNA file and Genespiral looks up rs2815752 along with every other marker in the Health & Wellness analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Obesity Risk in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs2815752 - NCBI
- rs2815752 variant page - Ensembl
- rs2815752 summary - SNPedia
- Clinical significance records for rs2815752 - ClinVar
- NEGR1 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.