rs7495174
HERC2rs7495174 is a single-nucleotide polymorphism (SNP) in the HERC2 gene. Genespiral reads it in the Appearance analysis to describe Eye Color.
- Gene
- HERC2
- Alleles
- A / G
- Genotypes
- AA, AG, GG
- Traits
- 1 trait across 1 analysis
An rsID such as rs7495174 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of AA, AG, GG. The order of the two letters carries no meaning, so AG and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Eye Color
Appearance · Part of the Appearance analysis
This SNP affects melanin production in the iris, contributing to eye color variation.
| Genotype | Association |
|---|---|
| AA | Brown Eyes |
| AG | Hazel/Green Eyes |
| GG | Blue Eyes |
- Summary
- Variations in HERC2 are linked to eye color ranging from blue to brown.
- Scientific insights
- 'GG' alleles are commonly associated with blue eyes, while 'AA' correlates with brown eyes.
- Lifestyle tips
- Eye color may be slightly influenced by environmental factors over time.
Check your genotype at rs7495174
Load your raw DNA file and Genespiral looks up rs7495174 along with every other marker in the Appearance analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Eye Color in your results.
Related
Other markers in HERC2
- rs12913832 - Eye Color
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs7495174 - NCBI
- rs7495174 variant page - Ensembl
- rs7495174 summary - SNPedia
- Clinical significance records for rs7495174 - ClinVar
- HERC2 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.