rs12913832
HERC2rs12913832 is a single-nucleotide polymorphism (SNP) in the HERC2 gene. Genespiral reads it in the Appearance analysis to describe Eye Color.
- Gene
- HERC2
- Alleles
- A / G
- Genotypes
- GG, AG, AA
- Traits
- 1 trait across 1 analysis
An rsID such as rs12913832 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of GG, AG, AA. The order of the two letters carries no meaning, so AG and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Eye Color
Appearance · Part of the Appearance analysis
Influences melanin production in the iris, affecting eye color.
| Genotype | Association |
|---|---|
| GG | Brown Eyes |
| AG | Hazel/Green Eyes |
| AA | Blue Eyes |
- Summary
- Strongly associated with eye color variations from blue to brown.
- Scientific insights
- Individuals with 'AA' are highly likely to have blue eyes, while 'GG' is associated with brown eyes.
- Lifestyle tips
- Eye color can slightly change over time due to environmental factors.
Check your genotype at rs12913832
Load your raw DNA file and Genespiral looks up rs12913832 along with every other marker in the Appearance analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Eye Color in your results.
Related
Other markers in HERC2
- rs7495174 - Eye Color
More markers from Appearance
Articles that discuss rs12913832
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs12913832 - NCBI
- rs12913832 variant page - Ensembl
- rs12913832 summary - SNPedia
- Clinical significance records for rs12913832 - ClinVar
- HERC2 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.