rs4646396
FGF5rs4646396 is a single-nucleotide polymorphism (SNP) in the FGF5 gene. Genespiral reads it in the Appearance analysis to describe Hair Density.
- Gene
- FGF5
- Alleles
- A / G
- Genotypes
- GG, GA, AA
- Traits
- 1 trait across 1 analysis
An rsID such as rs4646396 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of GG, GA, AA. The order of the two letters carries no meaning, so GA and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Hair Density
Appearance · Part of the Appearance analysis
Regulates hair growth cycles affecting density.
| Genotype | Association |
|---|---|
| GG | High Density |
| GA | Medium Density |
| AG | Medium Density |
| AA | Low Density |
- Summary
- Variations influence the number of hair follicles and overall hair fullness.
- Scientific insights
- The 'GG' genotype is linked to a fuller head of hair.
- Lifestyle tips
- Proper nutrition and scalp care can support hair density.
Check your genotype at rs4646396
Load your raw DNA file and Genespiral looks up rs4646396 along with every other marker in the Appearance analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Hair Density in your results.
Related
Other markers in FGF5
- rs201571 - Hair Shedding
- rs12565727 - Hair Thinning
More markers from Appearance
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs4646396 - NCBI
- rs4646396 variant page - Ensembl
- rs4646396 summary - SNPedia
- Clinical significance records for rs4646396 - ClinVar
- FGF5 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.