rs1799971
OPRM1rs1799971 is a single-nucleotide polymorphism (SNP) in the OPRM1 gene. Genespiral reads it in the Personality analysis to describe Pain Sensitivity.
- Gene
- OPRM1
- Alleles
- A / G
- Genotypes
- AA, AG, GG
- Traits
- 1 trait across 1 analysis
An rsID such as rs1799971 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of AA, AG, GG. The order of the two letters carries no meaning, so AG and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Pain Sensitivity
Physical Traits · Part of the Personality analysis
Involved in opioid receptors, affecting pain perception and response to analgesics.
| Genotype | Association |
|---|---|
| AA | Higher pain sensitivity |
| AG | Moderate pain sensitivity |
| GG | Lower pain sensitivity |
- Summary
- OPRM1 gene variations influence the body's response to pain and sensitivity to pain stimuli.
- Scientific insights
- Individuals with 'AA' may experience pain more intensely and may require higher doses of pain relief.
- Lifestyle tips
- Techniques like mindfulness and relaxation exercises can help manage pain sensitivity.
Check your genotype at rs1799971
Load your raw DNA file and Genespiral looks up rs1799971 along with every other marker in the Personality analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Pain Sensitivity in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs1799971 - NCBI
- rs1799971 variant page - Ensembl
- rs1799971 summary - SNPedia
- Clinical significance records for rs1799971 - ClinVar
- OPRM1 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.