rs73598374
ADArs73598374 is a single-nucleotide polymorphism (SNP) in the ADA gene. Genespiral reads it in the Sleep analysis to describe Deep Sleep Intensity.
- Gene
- ADA
- Alleles
- C / T
- Genotypes
- CC, CT, TT
- Traits
- 1 trait across 1 analysis
An rsID such as rs73598374 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of CC, CT, TT. The order of the two letters carries no meaning, so CT and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Deep Sleep Intensity
Sleep Quality · Part of the Sleep analysis
A functional ADA variant (c.22G>A) that slows adenosine breakdown, increasing slow-wave (deep) sleep pressure.
| Genotype | Association |
|---|---|
| CC | Typical slow-wave sleep |
| CT | Deeper, more efficient sleep |
| TT | Deeper, more efficient sleep |
- Summary
- The ADA variant is associated with more intense slow-wave sleep and higher sleep efficiency.
- Scientific insights
- Carriers of the 'T' allele tend to show deeper slow-wave sleep, higher sleep efficiency, and fewer awakenings than 'CC' individuals.
- Lifestyle tips
- Consistent sleep timing and limiting late-day caffeine support deep sleep regardless of genotype.
Check your genotype at rs73598374
Load your raw DNA file and Genespiral looks up rs73598374 along with every other marker in the Sleep analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Deep Sleep Intensity in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs73598374 - NCBI
- rs73598374 variant page - Ensembl
- rs73598374 summary - SNPedia
- Clinical significance records for rs73598374 - ClinVar
- ADA gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.