rs642961
IRF6 PER1rs642961 is a single-nucleotide polymorphism (SNP) in the IRF6 / PER1 gene. Genespiral reads it in the Appearance and Sleep analyses to describe Lip Thickness and Chronotype (Morning vs Evening Preference).
- Gene
- IRF6 / PER1
- Alleles
- A / G
- Genotypes
- AA, AG, GG
- Traits
- 2 traits across 2 analyses
An rsID such as rs642961 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of AA, AG, GG. The order of the two letters carries no meaning, so AG and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Lip Thickness
Appearance · Part of the Appearance analysis
Influences lip development and thickness.
| Genotype | Association |
|---|---|
| AA | Fuller Lips |
| AG | Moderate Fullness |
| GA | Moderate Fullness |
| GG | Thinner Lips |
- Summary
- Variations affect lip fullness and shape.
- Scientific insights
- The 'AA' genotype is associated with naturally fuller lips.
- Lifestyle tips
- Lip care products can enhance and maintain lip appearance.
Chronotype (Morning vs Evening Preference)
Sleep Patterns · Part of the Sleep analysis
Key regulator of circadian rhythm and daily activity patterns.
| Genotype | Association |
|---|---|
| AA | Morning preference |
| AG | Intermediate preference |
| GG | Evening preference |
- Summary
- Variations in PER1 gene are associated with an individual’s chronotype, or daily activity preference.
- Scientific insights
- 'AA' alleles are linked with morning preference, while 'GG' is linked with evening preference.
- Lifestyle tips
- Adjusting exposure to light can help shift your chronotype closer to desired timing.
Check your genotype at rs642961
Load your raw DNA file and Genespiral looks up rs642961 along with every other marker in the Appearance and Sleep analyses. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Lip Thickness and Chronotype (Morning vs Evening Preference) in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs642961 - NCBI
- rs642961 variant page - Ensembl
- rs642961 summary - SNPedia
- Clinical significance records for rs642961 - ClinVar
- IRF6 gene - NCBI Gene
- PER1 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.