rs2764264
FOXO3rs2764264 is a single-nucleotide polymorphism (SNP) in the FOXO3 gene. Genespiral reads it in the Aging & Longevity analysis to describe Longevity Potential.
- Gene
- FOXO3
- Alleles
- C / T
- Genotypes
- TT, CT, CC
- Traits
- 1 trait across 1 analysis
An rsID such as rs2764264 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of TT, CT, CC. The order of the two letters carries no meaning, so CT and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Longevity Potential
Longevity Markers · Part of the Aging & Longevity analysis
Regulates stress response and maintenance pathways.
| Genotype | Association |
|---|---|
| TT | Typical longevity profile |
| CT | Modest longevity association |
| CC | Slightly positive longevity association |
- Summary
- One of few replicated longevity-associated variants.
- Scientific insights
- Effect most notable in populations living to very advanced age.
- Lifestyle tips
- Lifestyle choices remain crucial for healthy aging.
Check your genotype at rs2764264
Load your raw DNA file and Genespiral looks up rs2764264 along with every other marker in the Aging & Longevity analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Longevity Potential in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs2764264 - NCBI
- rs2764264 variant page - Ensembl
- rs2764264 summary - SNPedia
- Clinical significance records for rs2764264 - ClinVar
- FOXO3 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.