rs1800012
COL1A1rs1800012 is a single-nucleotide polymorphism (SNP) in the COL1A1 gene. Genespiral reads it in the Aging & Longevity analysis to describe Collagen Production.
- Gene
- COL1A1
- Alleles
- A / C
- Genotypes
- CC, CA, AA
- Traits
- 1 trait across 1 analysis
An rsID such as rs1800012 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of CC, CA, AA. The order of the two letters carries no meaning, so CA and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Collagen Production
Dermatological Aging · Part of the Aging & Longevity analysis
Key structural collagen component.
| Genotype | Association |
|---|---|
| CC | Typical collagen production |
| CA | Slight variation in production |
| AA | Modified production pattern |
- Summary
- Influences collagen fiber organization.
- Scientific insights
- Multiple factors affect collagen production.
- Lifestyle tips
- Adequate protein and vitamin C support synthesis.
Check your genotype at rs1800012
Load your raw DNA file and Genespiral looks up rs1800012 along with every other marker in the Aging & Longevity analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Collagen Production in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs1800012 - NCBI
- rs1800012 variant page - Ensembl
- rs1800012 summary - SNPedia
- Clinical significance records for rs1800012 - ClinVar
- COL1A1 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.