rs2472297
CYP1A2rs2472297 is a single-nucleotide polymorphism (SNP) in the CYP1A2 gene. Genespiral reads it in the Miscellaneous Traits analysis to describe Caffeine Metabolism.
- Gene
- CYP1A2
- Alleles
- C / T
- Genotypes
- TT, TC, CC
- Traits
- 1 trait across 1 analysis
An rsID such as rs2472297 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of TT, TC, CC. The order of the two letters carries no meaning, so TC and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Caffeine Metabolism
Dietary Preferences · Part of the Miscellaneous Traits analysis
Influences how quickly caffeine is metabolized, affecting tolerance and sensitivity.
| Genotype | Association |
|---|---|
| TT | Fast Metabolizer |
| TC | Intermediate Metabolizer |
| CC | Slow Metabolizer |
- Summary
- CYP1A2 gene variations impact caffeine processing and related alertness effects.
- Scientific insights
- 'TT' genotype is associated with faster caffeine clearance from the system.
- Lifestyle tips
- Fast metabolizers may not experience strong effects from caffeine.
Check your genotype at rs2472297
Load your raw DNA file and Genespiral looks up rs2472297 along with every other marker in the Miscellaneous Traits analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Caffeine Metabolism in your results.
Related
Other markers in CYP1A2
- rs762551 - Caffeine Consumption
More markers from Miscellaneous Traits
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs2472297 - NCBI
- rs2472297 variant page - Ensembl
- rs2472297 summary - SNPedia
- Clinical significance records for rs2472297 - ClinVar
- CYP1A2 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.