rs182549
MCM6rs182549 is a single-nucleotide polymorphism (SNP) in the MCM6 gene. Genespiral reads it in the Miscellaneous Traits analysis to describe Lactose Tolerance.
- Gene
- MCM6
- Alleles
- C / T
- Genotypes
- CC, CT, TT
- Traits
- 1 trait across 1 analysis
An rsID such as rs182549 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of CC, CT, TT. The order of the two letters carries no meaning, so CT and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Lactose Tolerance
Dietary Preferences · Part of the Miscellaneous Traits analysis
Regulates lactase enzyme production, affecting ability to digest lactose.
| Genotype | Association |
|---|---|
| CC | Lactose Intolerant |
| CT | Lactose Tolerant |
| TT | Lactose Tolerant |
- Summary
- MCM6 gene variations influence lactose tolerance, especially in adulthood.
- Scientific insights
- 'TT' alleles are associated with lactose tolerance, commonly found in populations with a history of dairy consumption.
- Lifestyle tips
- Lactase supplements or lactose-free products can help manage intolerance.
Check your genotype at rs182549
Load your raw DNA file and Genespiral looks up rs182549 along with every other marker in the Miscellaneous Traits analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Lactose Tolerance in your results.
Related
Other markers in MCM6
- rs4988235 - Lactose Tolerance
More markers from Miscellaneous Traits
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs182549 - NCBI
- rs182549 variant page - Ensembl
- rs182549 summary - SNPedia
- Clinical significance records for rs182549 - ClinVar
- MCM6 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.