rs1042778
OXTRrs1042778 is a single-nucleotide polymorphism (SNP) in the OXTR gene. Genespiral reads it in the Personality analysis to describe Loneliness, Social Bonding, Willingness to Collaborate and Cooperative Behavior.
- Gene
- OXTR
- Alleles
- C / T
- Genotypes
- TT, TC, CC
- Traits
- 4 traits across 1 analysis
An rsID such as rs1042778 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of TT, TC, CC. The order of the two letters carries no meaning, so TC and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Loneliness
Emotional Traits · Part of the Personality analysis
Linked to oxytocin receptors, influencing social behaviors and feelings of loneliness.
| Genotype | Association |
|---|---|
| TT | Higher susceptibility to loneliness |
| TC | Moderate susceptibility |
| CC | Lower susceptibility |
- Summary
- OXTR variants can affect feelings of connection and susceptibility to loneliness.
- Scientific insights
- Individuals with 'TT' may feel more isolated, especially in social settings.
- Lifestyle tips
- Engaging in community activities and strengthening friendships can help reduce loneliness.
Social Bonding
Social Traits · Part of the Personality analysis
Influences oxytocin receptor function, affecting social bonding and trust.
| Genotype | Association |
|---|---|
| TT | Stronger social bonds |
| TC | Moderate social bonds |
| CC | Weaker social bonds |
- Summary
- Variations in the OXTR gene are associated with one's ability to form and maintain social bonds.
- Scientific insights
- Individuals with 'TT' may find it easier to build and maintain close relationships.
- Lifestyle tips
- Engaging in regular social activities can strengthen bonding skills and improve social connections.
Willingness to Collaborate
Social Traits · Part of the Personality analysis
Associated with oxytocin receptor function, impacting social bonding and collaborative tendencies.
| Genotype | Association |
|---|---|
| TT | More collaborative |
| TC | Moderately collaborative |
| CC | Less collaborative |
- Summary
- OXTR gene variations influence one's willingness and ease of working together with others.
- Scientific insights
- Individuals with 'TT' may be more inclined to collaborate and seek teamwork opportunities.
- Lifestyle tips
- Engaging in group activities can strengthen collaborative skills and team dynamics.
Cooperative Behavior
Social Traits · Part of the Personality analysis
Linked to oxytocin receptors, affecting social bonding, trust, and cooperation.
| Genotype | Association |
|---|---|
| TT | More cooperative |
| TC | Moderate cooperation |
| CC | Less cooperative |
- Summary
- Variations in the OXTR gene influence willingness to engage in cooperative behavior with others.
- Scientific insights
- Individuals with 'TT' may be more inclined to work with others and support group efforts.
- Lifestyle tips
- Participating in team activities and collaborative tasks can further enhance cooperative skills.
Check your genotype at rs1042778
Load your raw DNA file and Genespiral looks up rs1042778 along with every other marker in the Personality analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Loneliness and Social Bonding in your results.
Related
Other markers in OXTR
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs1042778 - NCBI
- rs1042778 variant page - Ensembl
- rs1042778 summary - SNPedia
- Clinical significance records for rs1042778 - ClinVar
- OXTR gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.