rs2241880
ATG16L1rs2241880 is a single-nucleotide polymorphism (SNP) in the ATG16L1 gene. Genespiral reads it in the Health & Wellness analysis to describe Crohn's Disease Risk.
- Gene
- ATG16L1
- Alleles
- A / G
- Genotypes
- AA, AG, GG
- Traits
- 1 trait across 1 analysis
An rsID such as rs2241880 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of AA, AG, GG. The order of the two letters carries no meaning, so AG and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Crohn's Disease Risk
Autoimmune and Inflammatory Conditions · Part of the Health & Wellness analysis
Involved in autophagy, affecting immune response in the digestive tract.
| Genotype | Association |
|---|---|
| AA | Increased Risk |
| AG | Moderate Risk |
| GG | Lower Risk |
- Summary
- ATG16L1 gene variations impact susceptibility to Crohn’s disease, an inflammatory bowel condition.
- Scientific insights
- 'AA' genotype may increase risk for Crohn’s disease, especially with family history.
- Lifestyle tips
- Dietary management and regular health check-ups are essential for managing Crohn’s risk.
Check your genotype at rs2241880
Load your raw DNA file and Genespiral looks up rs2241880 along with every other marker in the Health & Wellness analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Crohn's Disease Risk in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs2241880 - NCBI
- rs2241880 variant page - Ensembl
- rs2241880 summary - SNPedia
- Clinical significance records for rs2241880 - ClinVar
- ATG16L1 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.