rs2153271
BNC2rs2153271 is a single-nucleotide polymorphism (SNP) in the BNC2 gene. Genespiral reads it in the Appearance analysis to describe Freckles.
- Gene
- BNC2
- Alleles
- A / G
- Genotypes
- AA, AG, GG
- Traits
- 1 trait across 1 analysis
An rsID such as rs2153271 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of AA, AG, GG. The order of the two letters carries no meaning, so AG and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Freckles
Appearance · Part of the Appearance analysis
Regulates pigmentation, contributing to susceptibility to freckles.
| Genotype | Association |
|---|---|
| AA | More Likely to Have Freckles |
| AG | Moderate Likelihood |
| GG | Less Likely to Have Freckles |
- Summary
- BNC2 gene variations influence the presence and intensity of freckles.
- Scientific insights
- 'AA' genotype individuals have a higher likelihood of developing freckles, especially with sun exposure.
- Lifestyle tips
- Using sunscreen can help protect freckled skin from sun damage.
Check your genotype at rs2153271
Load your raw DNA file and Genespiral looks up rs2153271 along with every other marker in the Appearance analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Freckles in your results.
Related
Other markers in BNC2
- rs2158041 - Freckle Likelihood
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs2153271 - NCBI
- rs2153271 variant page - Ensembl
- rs2153271 summary - SNPedia
- Clinical significance records for rs2153271 - ClinVar
- BNC2 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.