rs10830963
MTNR1Brs10830963 is a single-nucleotide polymorphism (SNP) in the MTNR1B gene. Genespiral reads it in the Health & Wellness analysis to describe Fasting Glucose Regulation.
- Gene
- MTNR1B
- Alleles
- C / G
- Genotypes
- CC, CG, GG
- Traits
- 1 trait across 1 analysis
An rsID such as rs10830963 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of CC, CG, GG. The order of the two letters carries no meaning, so CG and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Fasting Glucose Regulation
Metabolic Disorders · Part of the Health & Wellness analysis
A melatonin-receptor (MTNR1B) variant that links night-time melatonin signalling to insulin release; the G allele is associated with higher fasting glucose and type 2 diabetes risk.
| Genotype | Association |
|---|---|
| CC | Lower fasting glucose tendency |
| CG | Intermediate |
| GG | Higher fasting glucose tendency |
- Summary
- MTNR1B genotype is a well-replicated influence on fasting blood glucose and diabetes risk.
- Scientific insights
- Each 'G' allele is associated with slightly higher fasting glucose, so 'GG' tends highest; the effect is modest.
- Lifestyle tips
- The effect is small; overall diet, weight, sleep timing, and activity dominate glucose control.
Check your genotype at rs10830963
Load your raw DNA file and Genespiral looks up rs10830963 along with every other marker in the Health & Wellness analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Fasting Glucose Regulation in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs10830963 - NCBI
- rs10830963 variant page - Ensembl
- rs10830963 summary - SNPedia
- Clinical significance records for rs10830963 - ClinVar
- MTNR1B gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.