rs10490924
ARMS2rs10490924 is a single-nucleotide polymorphism (SNP) in the ARMS2 gene. Genespiral reads it in the Aging & Longevity analysis to describe Age-related Macular Degeneration.
- Gene
- ARMS2
- Alleles
- G / T
- Genotypes
- GG, GT, TT
- Traits
- 1 trait across 1 analysis
An rsID such as rs10490924 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of GG, GT, TT. The order of the two letters carries no meaning, so GT and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Age-related Macular Degeneration
Sensory Aging · Part of the Aging & Longevity analysis
Associated with retinal health maintenance.
| Genotype | Association |
|---|---|
| GG | Typical risk |
| GT | Moderately increased risk |
| TT | Higher risk |
- Summary
- Well-studied variant affecting AMD risk.
- Scientific insights
- Risk modification possible through lifestyle choices.
- Lifestyle tips
- Regular eye exams and proper nutrition benefit all profiles.
Check your genotype at rs10490924
Load your raw DNA file and Genespiral looks up rs10490924 along with every other marker in the Aging & Longevity analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Age-related Macular Degeneration in your results.
Related
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs10490924 - NCBI
- rs10490924 variant page - Ensembl
- rs10490924 summary - SNPedia
- Clinical significance records for rs10490924 - ClinVar
- ARMS2 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.