rs6280
DRD3rs6280 is a single-nucleotide polymorphism (SNP) in the DRD3 gene. Genespiral reads it in the Personality analysis to describe Sociability in Novel Environments.
- Gene
- DRD3
- Alleles
- C / T
- Genotypes
- TT, CT, CC
- Traits
- 1 trait across 1 analysis
An rsID such as rs6280 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of TT, CT, CC. The order of the two letters carries no meaning, so CT and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Sociability in Novel Environments
Social Traits · Part of the Personality analysis
Associated with dopamine receptors influencing sociability and comfort in unfamiliar settings.
| Genotype | Association |
|---|---|
| TT | More sociable |
| CT | Moderate sociability |
| CC | Less sociable |
- Summary
- DRD3 gene variations may impact sociability and ease of interaction in new environments.
- Scientific insights
- Individuals with 'TT' may feel more comfortable and outgoing in novel social situations.
- Lifestyle tips
- Practicing social skills in new environments can help increase confidence and sociability.
Check your genotype at rs6280
Load your raw DNA file and Genespiral looks up rs6280 along with every other marker in the Personality analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Sociability in Novel Environments in your results.
Related
More markers from Personality
- rs4680 (COMT) - Pain Sensitivity and Extraversion
- rs6313 (HTR2A) - Emotional Sensitivity and Aggressiveness
- rs429358 (APOE) - Emotional Resilience and Risk of Memory Decline with Age
- rs1049353 (CNR1) - Conscientiousness and Self-Discipline
- rs2070116 (MAOA) - Impulsivity
- rs3792452 (SLC6A4) - Sensitivity to Musical Reward
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs6280 - NCBI
- rs6280 variant page - Ensembl
- rs6280 summary - SNPedia
- Clinical significance records for rs6280 - ClinVar
- DRD3 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.