rs1800955
DRD4rs1800955 is a single-nucleotide polymorphism (SNP) in the DRD4 gene. Genespiral reads it in the Personality and Learning & Cognition analyses to describe Sensation Seeking, Novelty Seeking, Sensitivity to Reward and Punishment, Responsiveness to Positive Feedback and ADHD Risk.
- Gene
- DRD4
- Alleles
- C / T
- Genotypes
- TT, TC, CC
- Traits
- 5 traits across 2 analyses
An rsID such as rs1800955 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of TT, TC, CC. The order of the two letters carries no meaning, so TC and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Sensation Seeking
Behavioral Traits · Part of the Personality analysis
Related to dopamine receptors that impact novelty-seeking and arousal levels.
| Genotype | Association |
|---|---|
| TT | Higher sensation seeking |
| TC | Moderate sensation seeking |
| CC | Lower sensation seeking |
- Summary
- DRD4 gene variations may contribute to thrill-seeking and preference for new experiences.
- Scientific insights
- Individuals with 'TT' may be drawn to high-intensity or novel activities.
- Lifestyle tips
- Channeling sensation-seeking tendencies into creative outlets can be beneficial.
Novelty Seeking
Behavioral Traits · Part of the Personality analysis
Associated with dopamine receptors, affecting responses to new and exciting stimuli.
| Genotype | Association |
|---|---|
| CC | Higher novelty seeking |
| CT | Moderate novelty seeking |
| TT | Lower novelty seeking |
- Summary
- DRD4 gene variations are linked to exploration and interest in novel experiences.
- Scientific insights
- Those with 'CC' may feel a strong drive to seek out new experiences and challenges.
- Lifestyle tips
- Engaging in hobbies that provide novelty can satisfy and balance novelty-seeking behavior.
Sensitivity to Reward and Punishment
Behavioral Traits · Part of the Personality analysis
Involved in dopamine receptor function affecting motivation, reward processing, and aversion.
| Genotype | Association |
|---|---|
| CC | Higher sensitivity |
| CT | Moderate sensitivity |
| TT | Lower sensitivity |
- Summary
- DRD4 gene variations can influence how strongly individuals respond to rewards and punishments.
- Scientific insights
- Individuals with 'CC' may have stronger emotional reactions to both rewards and negative feedback.
- Lifestyle tips
- Building emotional resilience can help manage sensitivity to rewards and punishments.
Responsiveness to Positive Feedback
Behavioral Traits · Part of the Personality analysis
Associated with dopamine receptors, impacting motivation and responsiveness to rewards and positive reinforcement.
| Genotype | Association |
|---|---|
| CC | More responsive |
| CT | Moderate responsiveness |
| TT | Less responsive |
- Summary
- DRD4 gene variations may influence how individuals respond to praise and positive reinforcement.
- Scientific insights
- Individuals with 'CC' may be more motivated by positive feedback and rewards.
- Lifestyle tips
- Setting reward-based goals can enhance motivation and performance.
ADHD Risk
Attention · Part of the Learning & Cognition analysis
Dopamine receptor gene associated with attention regulation.
| Genotype | Association |
|---|---|
| CC | Higher risk of ADHD |
| CT | Moderate risk |
| TT | Lower risk of ADHD |
- Summary
- Variations in the DRD4 gene can influence the risk of developing ADHD.
- Scientific insights
- Individuals with the 'CC' genotype may have a higher susceptibility to attention deficits.
- Lifestyle tips
- Structured routines and focus-enhancing activities can help manage attention challenges.
Check your genotype at rs1800955
Load your raw DNA file and Genespiral looks up rs1800955 along with every other marker in the Personality and Learning & Cognition analyses. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Sensation Seeking and Novelty Seeking in your results.
Related
More markers from Personality and Learning & Cognition
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs1800955 - NCBI
- rs1800955 variant page - Ensembl
- rs1800955 summary - SNPedia
- Clinical significance records for rs1800955 - ClinVar
- DRD4 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.