rs1800407
OCA2rs1800407 is a single-nucleotide polymorphism (SNP) in the OCA2 gene. Genespiral reads it in the Appearance analysis to describe Eye Color.
- Gene
- OCA2
- Alleles
- C / T
- Genotypes
- CC, CT, TT
- Traits
- 1 trait across 1 analysis
An rsID such as rs1800407 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of CC, CT, TT. The order of the two letters carries no meaning, so CT and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Eye Color
Appearance · Part of the Appearance analysis
Additional modifier of eye color, particularly influencing green or hazel tones.
| Genotype | Association |
|---|---|
| CC | Lighter Eyes |
| CT | Lighter Eyes |
| TT | Brown Eyes |
- Summary
- OCA2 variations may influence lighter eye colors in conjunction with other genes.
- Scientific insights
- 'CC' genotype can result in lighter eye colors, while 'TT' is associated with brown.
- Lifestyle tips
- Eye color can shift slightly with age or lighting exposure.
Check your genotype at rs1800407
Load your raw DNA file and Genespiral looks up rs1800407 along with every other marker in the Appearance analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Eye Color in your results.
Related
More markers from Appearance
- rs201571 (FGF5) - Hair Shedding
- rs1160312 (EDA2R) - Male Pattern Baldness
- rs2153271 (BNC2) - Freckles
- rs4646396 (FGF5) - Hair Density
- rs11098403 (ALX3) - Eye Shape
- rs12896399 (SLC24A4) - Hair Color Depth
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs1800407 - NCBI
- rs1800407 variant page - Ensembl
- rs1800407 summary - SNPedia
- Clinical significance records for rs1800407 - ClinVar
- OCA2 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.