rs16147
NPSR1rs16147 is a single-nucleotide polymorphism (SNP) in the NPSR1 gene. Genespiral reads it in the Personality analysis to describe Reaction to Fearful Stimuli.
- Gene
- NPSR1
- Alleles
- C / T
- Genotypes
- CC, CT, TT
- Traits
- 1 trait across 1 analysis
An rsID such as rs16147 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of CC, CT, TT. The order of the two letters carries no meaning, so CT and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Reaction to Fearful Stimuli
Emotional Traits · Part of the Personality analysis
Associated with the neuropeptide S receptor, influencing fear response and emotional regulation.
| Genotype | Association |
|---|---|
| CC | Stronger reaction |
| CT | Moderate reaction |
| TT | Weaker reaction |
- Summary
- NPSR1 gene variations can affect how strongly one reacts to fearful or threatening stimuli.
- Scientific insights
- Individuals with 'CC' may experience more intense emotional responses to fear-inducing situations.
- Lifestyle tips
- Techniques like exposure therapy and relaxation exercises can help manage fear responses.
Check your genotype at rs16147
Load your raw DNA file and Genespiral looks up rs16147 along with every other marker in the Personality analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Reaction to Fearful Stimuli in your results.
Related
Other markers in NPSR1
- rs3923809 - Restorative Sleep
More markers from Personality
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs16147 - NCBI
- rs16147 variant page - Ensembl
- rs16147 summary - SNPedia
- Clinical significance records for rs16147 - ClinVar
- NPSR1 gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.