rs1137101
LEPRrs1137101 is a single-nucleotide polymorphism (SNP) in the LEPR gene. Genespiral reads it in the Sleep analysis to describe Night Eating Syndrome (NES).
- Gene
- LEPR
- Alleles
- A / G
- Genotypes
- GG, GA, AA
- Traits
- 1 trait across 1 analysis
An rsID such as rs1137101 is the reference number dbSNP assigns to one position in the genome where people commonly differ by a single letter. Raw data exports from 23andMe and AncestryDNA list your two alleles at that position as a genotype - for this marker one of GG, GA, AA. The order of the two letters carries no meaning, so GA and its reverse are the same genotype.
Alleles on this page are written on the forward (plus) strand, matching how consumer raw files report them. Other references sometimes describe the same variant on the opposite strand, which swaps A↔T and C↔G - see why the same variant can look different. The associations below are educational summaries of published research; they are not diagnoses, and the effect of any single SNP is usually modest.
Night Eating Syndrome (NES)
Sleep Disorders · Part of the Sleep analysis
Linked to hunger signaling, affecting night eating tendencies.
| Genotype | Association |
|---|---|
| GG | Higher risk of NES |
| GA | Moderate risk |
| AA | Lower risk |
- Summary
- LEPR variations may increase the risk of experiencing NES.
- Scientific insights
- 'GG' is associated with a higher likelihood of night eating behaviors.
- Lifestyle tips
- Establishing a consistent meal schedule can help manage NES symptoms.
Check your genotype at rs1137101
Load your raw DNA file and Genespiral looks up rs1137101 along with every other marker in the Sleep analysis. The file is parsed in your browser and never uploaded, so your genotype stays on your device.
- 1. Download your raw data from 23andMe or AncestryDNA.
- 2. Open the analysis below and choose the file.
- 3. Find Night Eating Syndrome (NES) in your results.
Related
More markers from Sleep
- rs228697 (PER3) - Susceptibility to Sleep Deprivation
- rs1801260 (CLOCK) - Sleep-Wake Timing (Circadian Rhythm)
- rs1876828 (CRY1) - Sleep Fragmentation
- rs4684847 (CACNA1C) - Sleep Onset Latency
- rs7221412 (PER2) - Chronotype (Morning/Night)
- rs9382445 (CHRM2 / ABCC9) - REM vs NREM Sleep Architecture and Sleep Duration
References
Primary databases for this variant. Use them to check allele orientation, population frequencies, and the underlying studies.
- dbSNP entry for rs1137101 - NCBI
- rs1137101 variant page - Ensembl
- rs1137101 summary - SNPedia
- Clinical significance records for rs1137101 - ClinVar
- LEPR gene - NCBI Gene
Genespiral is an educational tool, not a medical service. Genetic associations describe tendencies observed across populations, not certainties for you. Read the full disclaimer.