Trait Analysis Without Uploading - 23andMe Alternatives

Ways to explore traits and SNPs without uploading your raw file to third party servers. Keep it local and stay in control.

You do not have to upload a raw DNA file to explore traits. Several approaches keep analysis on your device.

Options to consider

  • Browser based analysis that runs locally
  • Desktop viewers for text exports and simple SNP lookups
  • Lightweight notebooks for personal exploration

Why skip uploads

  • Reduce exposure and long term retention risk
  • Avoid unclear secondary uses of genetic data
  • Work at your own pace without wait times

Start by reading our guide to on device DNA analysis, then walk through the browser based analysis steps. When you are ready to try more, visit the blog for hands on examples.

Local first analysis is a simple change that improves privacy with almost no extra effort.

Example - quick local trait check

Create a tiny panel file panel.tsv with a few rsids and an effect allele, then filter your raw file locally:

# rsid	effect_allele
rs9939609	A
rs1800497	A
awk 'NR==FNR{a[$1]=1; next} !/^#/ && a[$1]' panel.tsv 23andme_raw.txt > subset.txt

Review the genotypes in a spreadsheet and keep notes. This keeps the workflow simple and avoids uploading sensitive data.

Good habits

  • Keep a private notes file with what you checked and why
  • Save a copy of your panel with sources for each rsid
  • When you are finished, remove intermediate files you do not need

Educational content only - not medical advice.

Further reading